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In the poor suburbs of Mexico City CIVA, a teenage girl, works for a drug cartel as a sicario (hit women). When Civa gets badly wounded during a brutal bloodbath she is unexpectedly rescued by RAFA, a middle-aged ostracized ex-cop. Together they go on the run from the cartel and form an unlikely friendship which leads Civa to reveal her true self to Rafa... She is a Aztec vampire known in ancient mythology as the lethal Civatateo, and she's on a path for revenge...