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The documentary Jeff Lowe's Metanoia traces the life and exploits of legendary mountaineer Jeff Lowe, from his visionary climbs around the world to his battle with an incurable neurological disease. The term "metanoia" means a fundamental shift in thinking or a transformation of the heart. In 1991, Jeff Lowe opened an incredible climbing route, called "Metanoia," on the north face of the Eiger in Switzerland, a feat that profoundly changed his life. This film recounts this exceptional adventure, which also becomes a metaphor for his battle with Lou Gehrig's disease (amyotrophic lateral sclerosis), which gradually caused him to lose all his physical abilities. A spiritual epic, Jeff Lowe, confronted with his own mortality, reveals his unique philosophy and inspiring creative genius, while showing his great inner strength in the face of adversity.