Seth MacFarlane

Stewie Griffin / Various Characters (voice)

Alex Borstein

Lois Griffin / Various Characters (voice)

Seth Green

Chris Griffin / Various Characters (voice)

Mila Kunis

Meg Griffin / Various Characters (voice)

Patrick Warburton

Joe Swanson (voice)

Lori Alan

Diane Simmons (voice)

Drew Barrymore

Drew Barrymore (voice)

Mike Henry

Cleveland Brown / John Herbert (voice)

Rachael MacFarlane

Katie Couric / Baby-Expecting Woman / Britney Spears (voice)

Noel Blanc

Elmer Fudd (voice)

Phil LaMarr

Ollie Williams /Various Characters (voice)

John G. Brennan

Horace / Additional Voices (voice)

Gary Janetti

Various Characters (voice)

Don LaFontaine

Promo Announcer (voice)

Ron Livingston

Clerk (voice)

Kevin Michael Richardson

Ray Charles / Various Characters (voice)

Kate Rigg

Various Characters (voice)

Will Sasso

Randy Newman / James Lipton (voice)

André Sogliuzzo

Various Characters (voice)

Rory Thost

Casper (voice)

John Viener

Meg 'Ron' Griffin (voice)

Adam West

Mayor Adam West (voice)

Wally Wingert

Various Characters (voice)

René Auberjonois

Odo (voice)

Ali Hillis

Meg Griffin (singing voice) / Various Characters (voice)

Ralph Garman

Various Characters (voice)

Jennie Garth

Kelly Taylor (voice)

Larry Kenney

Lion-O (voice)

Lynne Lipton

Cheetara (voice)

Jason Priestley

Brandon Walsh (voice)

Michael Clarke Duncan

The Stork (voice)

Chris Sheridan

Various Characters (voice)

Danny Smith

Al Harrington (voice)

Tori Spelling

Donna Martin (voice)

Joy Behar

Joy Behar (voice)

Fred Tatasciore

Various Characters (voice)

Adam Borstein

Various Characters (voice)

Bill Fagerbakke

Indian (voice)

David A. Goodman

Jesus Christ (voice)

Busy Philipps

Various Characters (voice)

Audrey Wasilewski

Various Characters (voice)