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Nasuda Ayumi is a young travel nurse who gives a bad first impression. In fact, he had been an excellent nurse practitioner in the US. He has the qualifications to carry out certain medical procedures and assist doctors in surgeries. However, some circumstances trigger his return to Japan where nurse practitioners are relatively unknown and nurses are still expected to do what doctors order. Ayumi ends up working at Amano General Medical Centre where he encounters a mysterious, legendary nurse Kuki Shizuka who will become his partner. Shizuka cleans “quietly” just like his name suggests and gets mistaken for a cleaner by the hospital staff including Ayumi. But he is actually a super nurse with boggling skills.