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Modern surgeon Qi Yue is transported to a parallel ancient world, where she becomes the murdered wife of a marquis. Struggling to survive and find a way back, she uses her medical skills to navigate political intrigue and personal challenges. As she learns traditional Chinese medicine and innovates new treatments, she unexpectedly falls for her husband, Chang Yuncheng. Facing betrayals, war, and epidemics, Qi Yue rises from an ordinary doctor to a legendary physician, leaving a lasting legacy.