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Jools Holland presents a mixture of live music. American indie-pop funsters We Are Scientists debut tracks from their forthcoming LP Brain Thrust Mastery. Political singer/songwriter Steve Earle performs with his wife Alison Moorer. Rising Nigerian star Asa sings her mix of pop, folk and reggae. Martina Topley Bird returns to the programme with tracks from her forthcoming album The Blue God, and Welsh female soul singer Duffy also performs.