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John and Denise Bruno have their hands full with their four girls. Dad's got issues with the two teenagers, Mariah (15) and Taylor (13), while Mom's fed up with the two youngest, Bella (6) and Sam (4). Mariah was born with fairly severe cerebral palsy and gets daily physical therapy from Mom, but she has no physical contact with Dad, as he no longer helps her out with her therapy. Mariah craves her dad's affection. John, a very traditional dad, doesn't approve of teen Taylor's punk-goth style and strong-will; they are constantly butting heads. The most difficult part of the day for Denise is when she's trying to do therapy with Mariah and the little ones interrupt and distract them. The girls' tantrums and demands have driven Denise to the end of her rope. Jo's faced with the challenge of saving Dad's relationships with the two oldest girls, especially Taylor, before they're too far gone, and getting Denise to demand respect from the little ones and keep them from interfering with her therapy time with Mariah.