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While in the midst of a Federal Tax Audit, Harborside Health Center's, Steve DeAngelo learns that the IRS intends to apply 280E, an obscure tax code that will label the dispensary as a Drug Trafficking organization,effectively put them out of business. As Steve and his crew prepare to fight back, The U.S. Justice department begins shutting down neighboring dispensaries. Could these two actions possibly be unrelated, or are the Feds launching a coordinated attack against Medical Marijuana? All the while, Steve's brother Andrew provides a helping hand to the father of an epileptic child as he administers Cannabis to his four-year old for the first time; and Jon, a patient-farmer struggles to save a harvest from a spider mite infestation.