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Centered around a young girl, Genocyber details the creation of the ultimate biological weapon, created out of two psychic sisters. Starting off in Hong Kong, the story follows a young mute girl who is unwittingly dragged into the ambitions of a mad scientist who wants to combine the powers of the girl and her crippled sister to activate the Genocyber itself. After a brutal search that leaves dozens of corpses in its wake, the search ends when the girl is apparently captured by agents of a shadowy government organization and the scientist arrested. This proves to be wrong however and the girl escapes, killing the scientist and government agents in the process.