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In the premiere of ITV's new medical drama. Martha and Robert's working relationship is called into jeopardy when, a patient makes it difficult for them to be honest with one another. As a result Robert's bipolar patient Joe goes AWOL and tragedy strikes. Elsewhere, when a model's agent tries to push her into getting cosmetic surgery Ekkow faces a moral dilemma. Should he perform the surgery or listen to the patient and decline. And, the practice is given the business opportunity of a lifetime but, will Robert's indiscretions jeopardise the deal.