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When a deadly virus escapes from a government research facility, few prove to be immune to its effects. With symptoms similar to the flu, those who come into contact with it quickly die. One survivor is Stu Redmond, a gas station attendant from Texas, who suffers no ill effects whatsoever. Kept in a medical research facility in Vermont, doctors try to determine why he is still alive. Others that also survive include Frannie Goldsmith who lives with her dad; Nick Andros, a deaf-mute; a rock musician, Larry Underwood; and Lloyd Henreid, in jail for murder. Survivors begin to have dreams, either about an old Afican-American woman, Mother Abigail, or a much scarier evil man.